Next-Gen Sequencing Cancer Panels
Speaker:
Colin Pritchard, MD, PhD
Contact Hours:
1.0
Date:
August 23, 2024 - August 31, 2026
Description:
Next-generation DNA sequencing methods allow simultaneous assessment of mutations in many genes at once. This technology is especially promising for cancer diagnostics, both for germline sequencing for hereditary cancer risk, and for tumor-based sequencing for precision cancer therapy. Since 2011, the University of Washington, Department of Laboratory Medicine, has offered clinical assays for cancer diagnostics using next-generation sequencing technology. This presentation reviews considerations related to clinical implementation of next-generation sequencing, and will cover cancer gene panels currently in clinical use for cancer patients and their families at Seattle Children's, UW, and SCCA.
Learning Objectives:
- Define next-generation sequencing and contrast this technology with traditional DNA sequencing approaches.
- Understand strengths and limitations of next-generation sequencing technology applied to clinical cancer genetics.
- List 3 types of genomic variation, and describe approaches to detect each type of variant using next-generation sequencing data.