Mitochondrial Fatty Acid Oxidation Defects
Speaker:
Michael J. Bennett, PhD, FRCPath, FACB, DABCC
Contact Hours:
1.0
Date:
April 22, 2025 - March 31, 2027
Description:
Genetic defects of mitochondrial fatty acid oxidation represent one of the most frequently found groups of inborn errors of metabolism. These disorders of fasting intolerance were primarily responsible for the expansion of newborn screening programs in the last decade. Our understanding of the significance of the pathway is still evolving and novel aspects of metabolic control and physiology will be described in this presentation.
Learning Objectives:
- Discuss current understanding of mitochondrial fatty acid oxidation
- Discuss long-chain defects and an unanticipated finding in one of them
- Describe a disorder of short/medium-chain FAO that plays a novel role in insulin secretion
- Introduce previously unrecognized roles for fatty acid oxidation